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Source-grounded intelligence on synbio and synbio funding, regulatory milestones, deployments, and policy.

Sep 14, 2026BREAKING

Cellectis Drops CAR-T for In Vivo Gene Editing

Cellectis exits lasme-cel and eti-cel, pivoting to TALE-based in vivo editing with 90% PCSK9 reduction in humanized mice.

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Sep 14, 2026BREAKING

Cellectis Drops lasme-cel, eti-cel for APOC3/PCSK9 Editing

Cellectis exits lasme-cel and eti-cel to focus on LNP-delivered APOC3 and PCSK9 editors; CLLS drops 41.61% on the news.

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Sep 13, 2026BREAKING

Teijin and Shinshu University Target CAR-T Mfg Gap in Japan

Teijin, Teijin Regenet, and Shinshu University Hospital form joint R&D pact to automate CAR-T manufacturing in Japan.

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Sep 12, 2026BREAKING

CRISPR Hits 100% Editing Efficiency in Lisianthus

Chinese researchers achieve 100% CRISPR editing efficiency in whole lisianthus plants, ending three decades of transformation failure.

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Sep 11, 2026RESEARCH

306 Gene-Editing Trials Tracked in CMN Q2 2026 Database

CMN Intelligence counts 306 publicly disclosed gene-editing trials as of July 2026, with the US and China leading by trial count.

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Sep 9, 2026RESEARCH

AstraZeneca 600-µL RoboColumns Match Bench Scale for bsAb Purification

AstraZeneca shows 600-µL RoboColumns match ~20-mL bench-scale chromatography for bsAb process characterization.

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Sep 8, 2026BREAKING

Editas Hires Dan Ory as CMO to Push EDIT-401 to Clinic

Editas Medicine names Dan Ory, M.D. as CMO to lead EDIT-401 clinical development for hyperlipidemia.

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Sep 4, 2026BREAKING

CTX310 CRISPR Cuts LDL 52.5% at 12 Months in Phase I

Cleveland Clinic's Phase I trial shows CTX310 CRISPR therapy cuts LDL 52.5% and triglycerides 47.8% at 12 months, zero serious adverse events.

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Sep 2, 2026RESEARCH

RT-qPCR Artifact Inflates CRISPR RNA Knockdown Data

A Nature Biotechnology study identifies a pervasive RT-qPCR artifact that systematically overstates RNA knockdown by CRISPR tools.

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Sep 1, 2026BREAKING

Beam Therapeutics Hires CCO Ahead of 2027 Risto-cel Launch

Beam Therapeutics names Eric Foster CCO as it targets a 2027 risto-cel launch, drawing on his $2.75B Horizon franchise record.

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Aug 31, 2026BREAKING

ArsenalBio Pivots to In Vivo CAR T, Cuts Workforce

ArsenalBio exits autologous solid tumor CAR-T, pivots to in vivo T cell therapy targeting hematologic and autoimmune disease.

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Aug 31, 2026BREAKING

CTX310 CRISPR Lipid Data Hold at 1 Year in NEJM

CTX310 CRISPR-Cas9 therapy targeting ANGPTL3 shows durable lipid reduction through 1 year, clearing path to phase 1b.

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Aug 31, 2026BREAKING

Nerai Bioscience Raises CHF 500K for AI CRISPR Engineering

Nerai Bioscience raised CHF 500K to build AI-driven CRISPR tool libraries targeting 8 rare disease pipelines from a University of Zurich spinout.

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Aug 28, 2026RESEARCH

CD19 CAR-T Puts Refractory RA Into Remission in Phase 1

Charité's COMPARE trial: 3 of 6 refractory RA patients in medication-free remission after single CD19 CAR-T infusion.

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Aug 28, 2026BREAKING

ÄIO and TFTAK Win €1.94M for Microbial Oil Fermentation

Estonian biotech ÄIO and TFTAK secure €1.94M to digitize microbial oil production from food and wood side-streams.

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Aug 28, 2026BREAKING

CTX310 Cuts LDL 53% With One Dose at One Year

Single CTX310 infusion sustains 53% LDL and 48% triglyceride reductions at one year in 15 patients — NEJM data published Aug 28.

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Aug 26, 2026BREAKING

$200 Bioreactor Kit Targets US Biomanufacturing Workforce Gap

BioMADE, Novonesis, and Iowa State are building a ~$200 bioreactor kit for high schools to close the biomanufacturing talent gap.

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Aug 25, 2026BREAKING

SynGenSys CHO.SET 2.0 Hits 4x Antibody Productivity

SynGenSys CHO.SET 2.0 synthetic promoters deliver over 4x antibody productivity and titers exceeding 2 g/L in fed-batch flask models.

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Aug 21, 2026FUNDING

IBioIC Awards £10,000 to Scale Biomanufacturing at 300 L Fermenter

IBioIC offers £10,000 grants to scale biobased processes at a 300 L Heriot-Watt fermenter. Applications closed Sept 1.

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Aug 20, 2026BREAKING

DSB-Free CRISPR: Base and Prime Editing Enter the Clinic

Third-generation gene editing ditches double-strand breaks, cutting genotoxicity risks that blocked CRISPR-Cas9 from broad clinical use.

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